Oroxin B( —— )

Catalog No. M17838 CAS No. 114482-86-9

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Datasheet

HNMR

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Product Name

Oroxin B
Note

Research use only, not for human use.
Brief Description

Oroxin B has antioxidant activity.
Description

Oroxin B has antioxidant activity.
In Vitro

RT-PCR Cell Line:Raji cells Concentration:0-40 μM Incubation Time:48 h Result:Decreased ER stress master genes (GRP78 and ATF6) mRNA level.
In Vivo

Animal Model:Human lymphoma cell (Raji cell) xenograft model Dosage:30 mg/kg Administration:i.p., 28 daysResult:Induced malignant lymphoma cell ER stress.Inhibited tumor growth.Prolonged overall survival of tumor-bearing mice.Animal Model:HFD-fed ratsDosage:200 mg/kg/day Administration:oral gavage Result:Reduced the levels of plasma lipids, LPS, IL-6, and TNF-α.Inhibited liver fibrosis by reducing collagen deposition.
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

Others-Field
Indication

——

CAS Number

114482-86-9
Formula Weight

594.52
Molecular Formula

C27H30O15
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (168.20 mM)
SMILES

c1(cc(=O)c2c(c(c(cc2o1)O[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)CO[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O)CO)O)O)c1ccccc1
Chemical Name

——

1. Li DQ,et al. Anal Bioanal Chem. 2014 Mar;406(7):1975-84.

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